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New Sorrento Mesa Bioterra Campus Completed by Longfellow in San Diego

Home » Buildings » Offices » New Sorrento Mesa Bioterra Campus Completed by Longfellow in San Diego

Longfellow Real Estate Partners has completed the Bioterra campus in the Sorrento Mesa submarket of San Diego, delivering approximately 323,000 square feet of Class-A life-science space. The development marks Longfellow’s first ground-up build in San Diego, positioning it to serve biotech and laboratory tenants with high-spec infrastructure and amenities. The project comes amid strong demand for lab space in the San Diego life-science market, particularly in the Sorrento Mesa and Sorrento Valley clusters.

Why Location and Design Matter in Sorrento Mesa

The Sorrento Mesa submarket is emerging as a key node for life-science tenants in San Diego, benefiting from proximity to research institutions and major transport links. The Bioterra campus, with its large floor plates and lab-ready infrastructure, enables flexible tenancy, from start-up scale to large occupiers. Moreover, the inclusion of a rooftop patio, fitness amenities and café elevates the tenant experience, supporting long-term lease appeal. Longfellow’s decision to design the building with all-electric HVAC and ESG-certified credentials addresses growing tenant demand for sustainability and operational efficiency.

Project Factsheet

Location: Oberlin Dr & Mira Mesa Blvd, Sorrento Mesa, San Diego, California, USA

Developer: Longfellow Real Estate Partners

Size: ~323,000 sq ft ground-up life-science campus

Site area: ~4.14 acres

Floors: 5-6 stories above grade, plus subterranean parking

Floor plates: ~50,000–70,000 sq ft flexible floor plates

Sustainability: Designed to LEED Gold and Fitwel standards; San Diego’s first all-electric HVAC life-science building

Amenities: Rooftop patio, fitness centre, café, conference spaces

Accessibility: Near major research institutes (UC San Diego, Salk, Scripps) and freeways I-5/I-805

Financing: ~US $202.6 million construction loan secured in December 2022

Market context: Delivered amidst high life-science market growth and tight lab vacancy in San Diego

Delivery timing: Completion noted in Q4 2024 according to market data

Tenant target: Biotech, research & development firms looking for premium lab-office space

Market Implications and Developer Strategy

By delivering Bioterra, Longfellow reinforces its leadership in life-science real-estate and deepens exposure in a strong growth market. The ~US $202 million financing suggests robust investor confidence in speculative lab developments in major clusters. For the San Diego market, the project adds significant new-build lab inventory just as vacancy remains at low levels and rental rates hold firm. Given the scale and amenity mix, Bioterra sets a new benchmark for life-science campuses in the region.

Outlook and Strategic Take-aways

As biotech and life-science companies expand in San Diego, purpose-built lab-office campuses like Bioterra are increasingly sought after. The project’s blend of flexibility, sustainability, and tenant-centric amenities positions it well for leasing momentum in the coming years. For Longfellow, the successful execution in Sorrento Mesa may pave the way for further ground-up development in other life-science growth markets. This trend aligns with broader investments in U.S. biomanufacturing, such as Gilead Sciences’ new manufacturing and R&D facility in California. Analysts will monitor lease-up pace, tenant mix, and how the project influences rent trajectories and lab-space supply in San Diego’s evolving ecosystem.

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