The Smilow Cancer Hospital at Greenwich Hospital officially began its major transformation with a ceremonial groundbreaking and wall-breaking on April 1, 2026. This project, which integrates advanced cancer care directly into the existing hospital campus, is scheduled for full completion in early 2029.
Greenwich Hospital is expanding its cancer treatment services after the town’s Planning and Zoning Commission unanimously approved a new Smilow Cancer Center on its Perryridge Road campus in 2025.
The center is being constructed in partnership with Yale New Haven Health and be an extension of Smilow Cancer Hospital and Yale Cancer Center, recognized as a national leader and the sole National Cancer Institute-designated Comprehensive Cancer Center in Connecticut.
Years in development, the project aims to bring advanced oncology services directly to Greenwich residents, eliminating the need for patients to travel to other cities for specialized treatment.
The Smilow Cancer Center expansion reflects a broader wave of U.S. hospital development, including major projects such as the $1.2 billion Roper Hospital campus in North Charleston, which recently moved into its vertical construction phase.
Expanded Services to Address Growing Cancer Rates
The new center will incorporate additional disease-specific teams in support of Greenwich’s current oncology specialists. The new center will deliver groundbreaking therapies, advanced technology, and patient-centered infusion areas. Yale New Haven Health says this new facility is arriving at a critical moment, with cancer diagnoses in the Greenwich area projected to rise over 10% in the 10-year period—specifically, for prostate, lung, liver, bladder, pancreatic, and skin cancer.
When completed, the new facility will augment the hospital’s existing oncology services, including diagnostic imaging, surgical services, private oncology suites, and specialized women’s cancer care. Together, the new and old amenities will be able to provide patients with more comprehensive, integrated care.
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Access to cancer care services
This new building will increase local cancer care services by a significant amount. It will have advanced radiation oncology suites and new therapies in patient-centered infusion spaces. Building on the current resources of Greenwich Hospital in oncology imaging, surgery, oncology private rooms, and women’s cancer, the center will offer a comprehensive and integrated treatment approach. Patients will benefit from multidisciplinary care teams, enrollment in over 300 clinical trials, healing environment, potentially including access to therapeutic garden.
The 59,000-square-foot renovation is currently moving through its primary construction phase, with a targeted completion date of early 2029. Architect Luke Voiland’s design for the project emphasizes a more cohesive site layout that increases green space by 30%, ensuring the expanded facility remains integrated with the surrounding neighborhood. Consigli Construction and Petra Construction Corporation are the key partners managing the build, which focuses on centralizing medical oncology, radiation, infusion, and surgical services into one unified healing campus.
A major component of this expansion was the recent debut of a 10,500-square-foot inpatient oncology suite. This 14-bed unit features all-private rooms designed with advanced infection prevention technology and dedicated areas for family members. This localized, cutting-edge facility will provide patients with direct access to pioneering research and clinical trials from the Yale Cancer Center, effectively meeting the region’s escalating demand for complex cancer care in a modern, compassionate setting.
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Smilow Cancer Hospital at Greenwich Hospital: Factsheet
Project Overview
- Total Investment: Estimated at $94 million.
- Fundraising Context: Part of the $125 million “Arc of Care” campaign.
- Total Size: Approximately 60,000 square feet of renovated space.
- Location: Centralized within the Watson and Cohen Pavilions at 5 Perryridge Road.
- Primary Goal: Providing a localized, one-stop destination for advanced cancer care to eliminate patient travel to New Haven or New York.
Timeline and Approvals
- Initial Project Announcement: February 2020.
- Planning Duration: Seven years of development, including multiple redesigns for community integration.
- Final Zoning Approval: Granted unanimously on July 1, 2025, by the Greenwich Planning and Zoning Commission.
- Official Construction Start: April 1, 2026.
- Projected Full Completion: Early 2029.
Key Milestones
- Landmark Donation: A $14 million gift from Lynne and Richard Pasculano to establish the radiation oncology center.
- Honoring Leadership: A $25 million anonymous grant awarded in 2026 to honor retired oncologist Dickerman Hollister Jr., MD.
- Construction Launch: Ceremonial “wall-breaking” event held in April 2026.
- First Phase Completion: Opening of the 10,500-square-foot inpatient oncology suite on April 28, 2026.
Clinical and Facilities Breakdown
- Specialized Units: Dedicated programs for breast, thoracic, gynecologic, and urologic cancers.
- Inpatient Capacity: 14 all-private rooms featuring advanced infection prevention and family zones.
- Infusion Services: 22 total stations (20 bays and two private suites) with direct views of the healing garden.
- Supportive Services: On-site specialized pharmacy and the Cingari Family Boutique for patient-specific wellness products.
- Research Access: The only regional program providing local access to Yale Cancer Center’s NCI-designated clinical trials.
Advanced Medical Technology
- Radiation Platforms: Installation of TrueBeam for image-guided radiotherapy and Vision RT for surface-guided treatments.
- Surgical Precision: Frameless radiosurgery capabilities for non-invasive, high-precision brain tumor treatment.
- Patient Comfort Tech: Specialized cooling cap chairs available to help minimize chemotherapy-induced hair loss.
Sustainability and Community Design
- Architectural Firm: Designed by SLAM Collaborative, featuring lead architect Luke Voiland.
- Green Space Enhancement: A 30% increase in landscaped areas and the creation of a new outdoor healing garden.
- Neighborhood Sensitivity: Increased building setbacks and centralized footprint to respect residential aesthetics.
- Infrastructure Upgrades: Extensive modifications to underground parking and site flow to mitigate local traffic impact.
Services Expansion
New Services:
- Groundbreaking cancer therapies
- Advanced diagnostic technology
- Specialized treatment programs
Enhanced Existing Services:
- Diagnostic imaging
- Surgical services
- Private oncology suites
- Women’s cancer care
Read also: Penn Medicine Expands Cancer Care With New Proton Therapy Center


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