The Tennessee Oncology flagship cancer center is a five story outpatient oncology building located at Elliston Place Plaza in Midtown Nashville, and it is now well past the construction phase. Patients have been treated there since July 2025, and the project went on to earn a 2026 Build Tennessee Award of Excellence from the Associated General Contractors of Tennessee.
Research Space Defines the Tennessee Oncology Elliston Place Plaza Center
The building now also serves as the corporate headquarters of OneOncology, Tennessee Oncology’s management partner, and developer Johnson HRE says it holds 60,000 square feet of clinical research and drug development space. That trial focus echoes Pfizer’s plans for a $650 million Groton manufacturing center that will supply medicines for clinical trials worldwide.
Project Overview
- Project Name: Tennessee Oncology Flagship Cancer Center at Elliston Place Plaza
- Location: 322 22nd Avenue North, Midtown Nashville, Tennessee
- Project Value: $120 million, according to Tennessee Oncology
- Client or Owner: Tennessee Oncology
- Main Contractor: Turner Construction
- Size: About 200,000 square feet across five floors above three underground parking levels; Gresham Smith puts the full building at about 310,000 square feet
- Key Components: Oncology and hematology clinics, imaging, infusion, Centers for Blood Cancers, and about 60,000 square feet of clinical research and drug development space
- Construction Start: Groundbreaking in July 2023
- Opening: July 2025
- Strategic Impact: Flagship site for a practice that treats nearly half of Tennessee’s cancer patients, per Tennessee Oncology, and home to OneOncology’s corporate headquarters
Project Team
- Owner: Tennessee Oncology
- General Contractor: Turner Construction
- Architect and Engineer: Gresham Smith
- Developer: Johnson HRE
- Construction Lender: Truist Bank
- Anchor Tenant: OneOncology
Reported 22nd October 2025: Turner Construction has completed a five-storey, 311,881 sq ft outpatient oncology facility in Nashville, Tennessee. The project marks a roughly US$105 million build for Tennessee Oncology, delivering advanced cancer-care services under one roof. The development consolidates imaging, medical oncology, radiation and surgical oncology in a single building. Construction included three underground parking levels and a full interior build-out of tenant space. This facility reflects a growing trend toward outpatient specialist centres in the healthcare construction sector.
Design, Execution and Operational Features
The project incorporated three overlapping scopes: core and shell, full interior fit-out and a specialised drug-development unit. Turner’s team coordinated multiple trade partners and phased scheduling across design and construction to maintain alignment. The facility emphasises patient-centric design: integrated navigation, support services and streamlined oncology workflows. The underground parking and above-ground medical offices deliver convenience and accessibility for patients and staff alike. The build is part of a broader strategy by Tennessee Oncology to offer community-based high-quality cancer care near where people live and work.
Project Factsheet
Location: 322 22nd Ave. N., Nashville, Tennessee, USA
Size: 311,881 square feet
Storeys: 5 above ground + 3 underground parking levels
Cost: Approximately US$105 million
Developer/Client: Tennessee Oncology
General Contractor: Turner Construction Nashville office
Design/Engineering: Gresham Smith
Developer Partner: Johnson Healthcare Real Estate
Financing: Construction loan by Truist Bank (approx. US$98.3 m)
Key Services Housed: Imaging, infusion, medical, radiation, surgical oncology; nutrition and support services
Strategic importance: Centralises cancer-care operations in the Nashville market and supports clinical trials and research
Target completion: Facility opened in late 2025 for service delivery across Middle Tennessee.
Market Implications and Regional Significance
This development signals confidence in outpatient healthcare infrastructure even amid cautious construction markets. The medical office building (MOB) sector has faced subdued activity, yet this project demonstrates demand for advanced specialist care centres. The Nashville region benefits as one of the fastest-growing healthcare markets in the Southeast, with this build placing Tennessee Oncology and Turner Construction at the forefront. The facility’s consolidation of multiple specialties supports cost-effective care delivery while enhancing patient experience. From a construction industry viewpoint, the project showcases effective management of complex healthcare construction, balancing shell, fit-out and high-tech requirements.
Outlook and Strategic Takeaways
With full completion in late 2025, Tennessee Oncology’s centre is poised to elevate care delivery across Middle Tennessee. The facility’s integration of clinical, surgical, and research capabilities underscores how healthcare providers are moving toward one-stop campuses. For Turner Construction, this project adds to its healthcare portfolio at a time when managing complex outpatient builds demands specialised expertise. The case highlights that in healthcare real estate, investment continues even as broader commercial building remains uncertain. Similar momentum is seen in Georgia, where Wellstar Health has received approval for its $1 billion Acworth Hospital, as providers prioritise patient experience, operational efficiency, and innovation—driving the rise of purpose-built MOBs across the U.S.
Leave a Reply