New facility aims to expand healthcare capacity in one of Tennessee’s fastest-growing regions.
Ascension Saint Thomas has broken ground on a $148.5 million hospital and healthcare campus in Clarksville, launching a major project intended to expand medical services and support the rapidly growing population of Montgomery County.
Healthcare leaders, local officials, physicians and community partners gathered Tuesday for the groundbreaking ceremony, marking the start of construction on the 96-acre development near the intersection of Highway 76 and Interstate 24.
The project will be anchored by a new full-service hospital that will initially open with 44 inpatient beds. The facility has been designed with future growth in mind. And can expand to accommodate up to 132 beds as demand increases.
Broad Range of Medical Services Planned
According to project details, the hospital will offer emergency care, inpatient surgical services, cardiology, neurosciences, women’s health, neonatal intensive care, oncology and orthopaedics.
The wider healthcare campus is planned as an integrated medical hub, bringing together physician practices, specialty care providers, outpatient services and rehabilitation facilities in a single location.
Partners expected to operate on the campus include Tennessee Oncology, Tennessee Orthopaedic Alliance, Ascension Saint Thomas Heart and Howell Allen Clinic. An inpatient rehabilitation hospital will also be developed in partnership with Lifepoint Health.
In addition, Montgomery County is collaborating with the project through a public-private partnership that will establish a new ambulance and emergency medical services station on the campus.
Investment Supports Regional Growth
The development comes as Clarksville and Montgomery County continue to experience significant population and economic growth, increasing demand for healthcare infrastructure and services.
Local officials said the project will improve access to care for residents while helping position the region for future expansion.
Construction is expected to begin immediately following the groundbreaking, with additional details regarding timelines and service openings to be announced as the project advances.
Economic Impact
Beyond healthcare access, the development is expected to generate substantial economic benefits for the region.
Project estimates indicate the hospital will create approximately 250 jobs once operational. The broader economic impact is projected at roughly $316 million annually. While supporting more than 1,300 direct and indirect jobs across the regional economy.
Ascension Saint Thomas has maintained a presence in the Clarksville area since opening its first local facility in 2005 and currently operates 17 care locations throughout Montgomery County.
Additionally, Clarksville project is one of several major hospital developments now under construction nationwide, alongside HSHS St. Mary’s Hospital Medical Center in Green Bay, where demolition has begun on the North Building as part of a $270 million campus upgrade.

Fact Sheet: Ascension Saint Thomas New Full-Service Hospital and Health Campus in Clarksville
Location: Clarksville, Tennessee
Investment: $148.5 million
Site Size: 96 acres
Hospital Capacity at Opening: 44 inpatient beds
Future Capacity: Expandable to 132 inpatient beds
Planned Services: Emergency care, inpatient surgery, cardiology, neurosciences, women’s health, neonatal intensive care, oncology and orthopaedics
Healthcare Partners:
Tennessee Oncology
Tennessee Orthopaedic Alliance
Ascension Saint Thomas Heart
Howell Allen Clinic and Lifepoint Health
Additional Facilities: Inpatient rehabilitation hospital, outpatient surgery center, advanced imaging facilities, specialty ambulatory care services and EMS station
Expected Hospital Employment: Approximately 250 jobs
Estimated Annual Economic Impact: $316 million
Total Jobs Supported: More than 1,300 direct and indirect jobs
Construction Status: Groundbreaking completed; construction set to begin immediately
Developer/Operator: Ascension Saint Thomas

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